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Alexander Poulev
(Александър Пулев)
Assistant Research Professor
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Work phones: 848 932 6266; 848 932 6342
Александьр Пулев
SEBS
  • Graduated as Magister of Pharmacy from the Faculty of Pharmacy at the Medical Academy in Sofia, Bulgaria. Ph. D. in Pharmacognosy (Dr. rer. nat., Dissertation) from the Ludwig Maximilian University of Munich, Germany, 1992.
  • Interests in the field of plant cell culture development, preferably from medicinal plants, induction of bioactive natural product biosynthesis, identification, isolation, purification. Developed radio- and enzymeimmunoassays for the quantitation of Galanthamine, an Amaryllidaceae alkaloid with potent reversible acetylcholinesterase inhibiting activity. Galanthamine HBr is commercially available as Nivalin®. Established immunoassays for quantitation of Colchicine, which is a water soluble alkaloid with cytotoxic activity, present in several species of Liliaceae. Isolated soil microorganisms capable of highly efficient regioselective demethylation at C-3 of the Colchicine structure - an important reaction toward semi-synthetical modification of the molecule, aimed to the synthesis of less toxic derivatives.
  • Participated in the development of a pilot scale plant cell culture-based process for the production of Paclitaxel - complex diterpen structure with anticancer activity. This compound was approved by the FDA for treatment of certain types of cancer, and commercialized by the Bristol Myers Squibb Company under the name of Taxol®.
  • Developed novel processes for commercially feasible purification and production of natural products with potent anticancer activity (patents issued). Established analytical HPLC methods for qualitative and quantitative determination of natural products. Developed preparative HPLC methods for product isolation. Developed MPLC and large scale column separation methods for product isolation and purification.
  • As a member of Dr. I. Raskin's group in the Department of Plant Biology and Pathology at SEBS, Rutgers, he is developing analytical and preparative methods utilizing HPLC, UPLC, LC-MS, and LC-MS/MS techniques for separation and identification of pharmacologically valuable natural products in plant material. Participated in the structural elucidation of two biologically active compounds with plant origin not reported previously in the literature. Key member of the drug discovery group.


Publications, patents, & poster presentations:

  1. Rebello, C., Greenway, F., Johnson, W., Ribnicky, D., Poulev, A., Stadler, K., Coulter, A. Fucoxanthin and its metabolite fucoxanthinol do not induce browning in human adipocytes. J. Agric. Food Chem., submitted, 2017.
  2. Cheng, D. M., Roopchand, D. E., Poulev, A., Kuhn, P., Armas-Gutierez, I., Johnson, W. D., Oren, A., Ribnicky, D., Zelzion, E., Bhattacharya, D., Raskin, I. High phenolics Rutgers Scarlet Lettuce improves glucose metabolism in high fat diet-induced obese mice. Mol. Nutr. Food Res., Vol. 60, No. 11, pp. 2367-2378, 2016.
  3. Graf, B., Rojo, L., Delatorre-Herrera, J., Poulev, A., Del Pilar Calfio, C., and Raskin, I. Phytoecdysteroids and flavonoid glycosides among Chilean and commercial sources of Chenopodium quinoa: variation and correlation to physicochemical characteristics. J. Sci. Food Agric., Vol. 96, No. 2, pp. 633-643, 2016.
  4. T. B. Tümer, P. Rojas-Silva, A. Poulev, I. Raskin, and C. Waterman. Direct and Indirect Antioxidant Activity of Polyphenol and Isothiocyanate-Enriched Fractions from Moringa oleifera. J. Agric. Food Chem., Vol. 63, No. 5, pp. 1505-1513, 2015.
  5. B. L. Graf, Cheng, D. M., Esposito, D., Shertel, T., Poulev, A., Plundrich, N., Itenberg, D., Dayan, N., Lila, M. A., and I. Raskin. Compounds leached from quinoa seeds inhibit matrix metalloproteinase activity and intracellular reactive oxygen species. International Journal of Cosmetic Science, Vol. 37, No. 2, pp. 212-221, 2015.
  6. Nebojša Ilić, Moul Dey, Alexander Poulev, Sithes Logendra, Peter Kuhn, and Ilya Raskin. Anti-inflammatory activity of Grains of paradise (Aframomum melegueta Schum) extract. J. Agric. Food Chem., Vol. 62, No. 43, pp. 10452-7, 2014.
  7. B. L. Graf, A. Poulev, P. Kuhn, M. H. Grace, M. A. Lila, and I. Raskin. Quinoa seeds leach phytoecdysteroids and other compounds with anti-diabetic properties. Food Chemistry, Vol. 163, pp. 178-185, 2014.
  8. C. Waterman, D. M. Cheng, P. Rojas-Silva, A. Poulev, J. Dreifus, M. A. Lila, I. Raskin. Stable, water extractable isothiocyanates from Moringa oleifera leaves attenuate inflammation in vitro. Phytochemistry, Vol. 103, pp. 114-122, April 2014.
  9. D. M. Ribnicky, D. E. Roopchand, A. Poulev, P. Kuhn, A. Oren, W. T. Cefalu, I. Raskin. Artemisia dracunculus L. polyphenols complexed to soy protein show enhanced bioavailability and hypoglycemic activity in C57BL/6 mice. Nutrition, Vol. 30, No. 7-8, Supplement, pp. S4-S10, 2014.
  10. D. M. Cheng, N. Pogrebnyak, P. Kuhn, A. Poulev, C. Waterman, P. Rojas-Silva, W. D. Johnson, and I. Raskin. Polyphenol-Rich Rutgers Scarlet Lettuce Improves Glucose Metabolism and Liver Lipid Accumulation in Diet Induced Obese C57BL/6 Mice. Nutrition, Vol. 30, No. 7-8, Supplement, pp. S52-S58, 2014.
  11. Ribnicky, D. M., Roopchand, D. E., Oren, A., Grace, M., Poulev, A., Lila, M. A., Havenaar, R., and I. Raskin. Effects of a high fat meal matrix and protein complexation on the bioaccessibility of blueberry anthocyanins using the TNO gastrointestinal model (TIM-1). Food Chemistry, Vol. 142, No. 1, pp. 349-357, 2014.
  12. P. Rojas-Silva, R. Graziose, B. Vesely, A. Poulev, F. Mbeunkui, M. H. Grace, D. E. Kyle, M. A. Lila, and I. Raskin. Leishmanicidal activity of a daucane sesquiterpene isolated fromEryngium foetidum. Pharmaceutical Biology, Vol. 52, No. 3, pp. 398-401, 2014.
  13. S. Komarnytsky, D. Esposito, Th. Rathinasabapathy, A. Poulev, and I. Raskin. Effects of Pregnane Glycosides on Food Intake Depend on Stimulation of Melanocortin Pathway and BDNF in Animal Model. J. Agric. Food Chem., Vol. 61, No. 8, pp. 1841-1849, 2013.
  14. R. Graziose, M. H. Grace, Th. Rathinasabapathy, P. Rojas-Silva, C. Dekock, A. Poulev, M. A. Lila, P. Smith, and I. Raskin. Antiplasmodial activity of cucurbitacin glycosides from Datisca glomerata (C. Presl) Baill. Phytochemistry, Vol. 87, pp. 78-85, March 2013.
  15. Komarnytsky, S., D. Esposito, A. Poulev, and I. Raskin. Pregnane glycosides interfere with steroidogenic enzymes to down-regulate corticosteroid production in human adrenocortical H295R cells. J. Cell Physiol., Vol. 228, No. 5, pp. 1120-1126, 2013.
  16. D. M. Cheng, P. Kuhn, A. Poulev, L. E. Rojo, M. A. Lila and I. Raskin. In Vivo and In Vitro Antidiabetic Effects of Aqueous Cinnamon Extract and Cinnamon Polyphenol-Enhanced Food Matrix. Food Chemistry, Vol. 135, No. 4, pp. 2994-3002, 2012.
  17. Graziose, R., Rojas-Silva, P., Rathinasabapathy, Th., Dekock, C., Grace, M. H., Poulev, A., Lila, M. A., Smith, P., and I. Raskin. Antiparasitic compounds from Cornus florida L. with activities against Plasmodium falciparum and Leishmania tarentolae. J. of Ethnopharmacology, Vol. 142, No. 2, pp. 456-461, 2012.
  18. Roopchand, D. E., P. Kuhn, A. Poulev, A. Oren, M. A. Lila, B. Fridlender and I. Raskin. Biochemical analysis and in vivo hypoglycemic activity of a grape polyphenol-soybean flour complex. J. Agric. Food Chem., Vol. 60, No. 36, pp. 8860-8865, 2012.
  19. Roopchand, D. E., M. H. Grace, P. Kuhn, D. M. Cheng, N. Plundrich, A. Poulev, A. Howell, B. Fridlender, M. A. Lila, I. Raskin. Efficient sorption of polyphenols to soybean flour enables natural fortification of foods. Food Chemistry, Vol. 131, No. 4, pp.1193-1200, 2012.
  20. Rojo, L., Ribnicky, D., Logendra, S., Poulev, A., Rojas, P., Kuhn, P., Dorn, R., Grace, M., Lila, M. A., and I. Raskin. In vitro and in vivo anti-diabetic effects of anthocyanins from Maqui Berry (Aristotelia chilensis). Food Chemistry, Vol. 131, No. 2, pp. 387-396, 2012.
  21. Eisenman, S. W., Poulev, A., Struwe, L., Ribnicky, D. M., and I. Raskin. Qualitative variation of anti-diabetic compounds in different wild tarragon (Artemisia dracunculus L.) cytotypes. Fitoterapia, Vol. 82, No. 7, pp. 1062-1074, 2011.
  22. Esposito, D., Rathinasabapathy, Th., Poulev, A., Komarnytsky, S., Raskin, I. Akt-dependent anabolic activity of natural and synthetic brassinosteroids in rat skeletal muscle cells. J. Med. Chem., Vol. 54, No. 12, pp. 4057-4066, 2011.
  23. Graziose, R., Rathinasabapathy, Th., Lategan, C., Poulev, A., Smith, P. J., Grace, M., Lila, M. A., and I. Raskin. Antiplasmodial activity of aporphine alkaloids and sesquiterpene lactones from Liriodendron tulipifera L. J. of Ethnopharmacology, Vol. 133, No. 1, pp. 26-30, 2011.
  24. Wang, Z. Q., Zhang, X. H., Yu, Y., Poulev, A., Ribnicky, D., and W. T. Cefalu. Bioactives from bitter melon enhance insulin signaling and modulate acyl carnitine content in skeletal muscle in high-fat diet fed mice. J. Nutr. Biochem., Vol. 22, No. 11, pp. 1064-1073, 2011.
  25. N. Ilić, B. Schmidt, A. Poulev, I. Raskin. Toxicological evaluation of Grains of Paradise (Aframomum melegueta) [Roscoe] K. Schum. J. Ethnopharmacology, Vol. 127, No. 2, pp. 352-356, 2010.
  26. D. M. Ribnicky, P. Kuhn, A. Poulev, S. Logendra, A. Zuberi, W. T. Cefalu, and I. Raskin. Improved absorption and bioactivity of active compounds from an anti-diabetic extract of Artemisia dracunculus L. International Journal of Pharmaceutics, Vol. 370, Nos. 1-2, pp. 87-92, 2009.
  27. M. H. Grace, D. M. Ribnicky, P. Kuhn, A. Poulev, S. Logendra, G. Yousef, I. Raskin, and M. A. Lila. Hypoglycemic activity of a novel anthocyanin-rich formulation from lowbush blueberry, Vaccinium angustifolium Aiton. Phytomedicine, Vol. 16, No. 5, 406-415, 2009.
  28. J. Gorelick-Feldman, D. Maclean, N. Ilić, A. Poulev, M. A. Lila, D. Cheng, and I. Raskin. Phytoecdysteroids Increase Protein Synthesis in Skeletal Muscle Cells. J. Agric. and Food Chem., Vol. 56, No. 10, pp. 3532-3537, 2008.
  29. Laura K. Stewart, Jeff L. Soileau, David Ribnicky, Zhong Q. Wang, IIya Raskin, Alexander Poulev, Martin Majewski, William T. Cefalu, and Thomas W. Gettys. Quercetin Increases Energy Expenditure and Decreases Circulating Markers of Inflammation in C57BL/6J Mice Fed a High Fat Diet, Metabolism, Clinical and Experimental Vol. 57, Suppl. 1, pp. S39-S46, 2008.
  30. Barbara Schmidt, David M. Ribnicky, Alexander Poulev, Sithes Logendra, William T. Cefalu and Ilya Raskin. A Natural History of Botanical Therapeutics. Metabolism, Clinical and Experimental, Vol. 57, Suppl. 1, pp. S3-S9, 2008.
  31. Ribnicky, D. M., B. Schmidt, A. Poulev, W. T. Cefalu, and I. Raskin. Evaluation of botanicals for improving human health. Am. J. Clin. Nutr., Vol. 87(suppl), No. 2, pp. 472S-475S, 2008.
  32. Ma, J., B. M. Schmidt, A. Poulev, I. Raskin. Determination of tripdiolide in root extracts of Tripterygium wilfordii by solid phase extraction and reversed phase high performance liquid chromatography. Phytochemical Analysis, Vol. 19, No. 4, pp. 348-352, 2008.
  33. Dmitry Govorko, Sithes Logendra, Yanxin Wang, Debora Esposito, David Ribnicky, Alexander Poulev, William T. Cefalu, and Ilya Raskin. Polyphenolic Compounds from Artemisia dracunculus L. Inhibit PEPCK Gene Expression and Gluconeogenesis in an H4IIE Hepatoma Cell Line. AJP: Endocrinology and Metabolism, Vol. 293, No. 6, pp. E1503-10, Dec. 2007.
  34. Ma, J., Dey, M., Yang, H., Poulev, A., Pouleva, R., Dorn, R., Lipsky, P., Kenelly, E. J., and Raskin, I. Anti-inflammatory and immunosuppressive compounds from Tripterygium wilfordii. Phytochemistry, Vol. 68, No. 8, pp. 1172-1178, 2007.
  35. Christopher Okunji, Slavko Komarnytsky, Georgie Fear, Alexander Poulev, David M. Ribnicky, Peter I. Awachie, Yoichiro Ito, and Ilya Raskin. Preparative isolation and identification of tyrosinase inhibitors from the seeds of Garcinia kola by high-speed counter-current chromatography. J. of Chromatography A, Vol. 1151, Nos. 1-2, 45-50, 2007.
  36. Schmidt, B. M., N. Ilić, A. Poulev, and I. Raskin. Toxicological evaluation of a chicory root extract. Food Chem. Tox., Vol. 45, No. 7, 1131-1139, 2007.
  37. Ripoll, C., B. Schmidt, N. Ilić, A. Poulev, M. Dey, A. G. Kurmukov, and I. Raskin. Anti-inflammatory effects of a sesquiterpene lactone extract from chicory (Cichorium intybus L.) roots. Natural Product Communications, Vol. 2, No. 7, 717-722, 2007.
  38. S. Logendra, D. M. Ribnicky, H. Yang, A. Poulev, J. Ma, E. J. Kennelly, and I. Raskin. Bioassay-guided fractionation and isolation of aldose reductase inhibitors from Artemisia dracunculus. Phytochemistry, Vol. 67, No. 14, pp. 1539-1546, 2006.
  39. Moreno, D. A., Ilić, N., Poulev, A., Raskin, I. Effects of Arachis hypogaea nutshell extract on lipid metabolic enzymes and obesity parameters. Life Sciences, Vol. 78, No. 24, pp. 2797-2803, 2006.
  40. Moreno, D. A., Ripoll, C., Ilić, N., Poulev, A., Aubin, C., Raskin, I. Inhibition of lipid metabolic enzymes using Mangifera indica extracts. J. Food Agric. & Environ., Vol. 4, No. 1, 21-26, 2006.
  41. David M. Ribnicky, Alexander Poulev, Malcolm Watford, William T. Cefalu, and Ilya Raskin. Antihyperglycemic Activity of TARRALIN™, an Ethanolic Extract of Artemisia dracunculus L. Phytomedicine, Vol. 13, No. 8, 550-557, 2006.
  42. David M. Ribnicky, Alexander Poulev, Joseph O'Neal, Gary Wnorowski, Dolores E. Malek, Ralf Jäger, Ilya Raskin. Toxicological Evaluation of the Ethanolic Extract of Artemisia dracunculus L. for Use as a Dietary Supplement and in Functional Foods. Food and Chemical Toxicology, Vol. 42, No. 4, pp. 585-598, 2004.
  43. Diego A. Moreno, Nebojša Ilić, Alexander Poulev, Dawn L. Brasaemle, Susan K. Fried, Ilya Raskin. Inhibitory effects of grape seed extract on lipases. Nutrition, Vol. 19, No. 10, pp. 876-879, 2003.
  44. A. Poulev, J. M. O'Neal, S. Logendra, R. B. Pouleva, V. Timeva, A. S. Garvey, D. Gleba, I. S. Jenkins, B. T. Halpern, R. Kneer, G. M. Cragg, and I. Raskin. Elicitation, a new window into plant chemodiversity and phytochemical drug discovery. J. Med. Chem., Vol. 46, No. 12, pp. 2542-2547, 2003.
  45. Ribnicky, D. M., A. Poulev, and I. Raskin. The determination of salicylates in Gaultheria procumbens for use as a natural Aspirin alternative. Journal of Nutraceuticals, Functional and Medical Foods. Vol. 4, No. 1, pp. 39-52, 2003.
  46. Ilya Raskin, David M. Ribnicky, Slavko Komarnytsky, Nebojša Ilić, Alexander Poulev, Nikolai Borisjuk, Anita Brinker, Diego A. Moreno, Christophe Ripoll, Nir Yakoby, Joseph M. O'Neal, Teresa Cornwell, Ira Pastor and Bertold Fridlender. Plants and human health in the twenty-first century. Trends in Biotechnology, Vol. 20, No. 12, pp. 522-531, 2002.
  47. Shen, Z.-W., U. Fisinger, A. Poulev, W. Eisenreich, I. Werner, E. Pleiner, A. Bacher, and M. H. Zenk. Tracer Studies With 13C-labeled Carbohydrates in Cultured Plant Cells. Retrobiosynthetic Analysis of Chelidonic Acid Biosynthesis. Phytochemistry, Vol. 57, No. 1, pp. 33-42, 2001.
  48. Ribnicky, D. M., A. Poulev, E. Henry, and I. Raskin. Seed of Barbarea verna as a Rich Source of Phenethyl Isothiocyanate to Provide Natural Protection from Environmental and Dietary Toxins. Journal of Nutraceuticals, Functional and Medical Foods. Vol. 3, No. 3, pp. 43-65, 2001.
  49. Leizer, C., D. M. Ribnicky, A. Poulev, S. Dushenkov, and I. Raskin. The Composition of Hemp Seed Oil and its Potential as an Important Source of Nutrition. Journal of Nutraceuticals, Functional and Medical Foods. Vol. 2, No. 4, pp. 35-53, 2000.
  50. Kneer, R., Poulev, A., Olesinski, A., and Raskin, I. Characterization of the Elicitor-induced Biosynthesis and Secretion of Genistein from Roots of Lupinus luteus L. Journal of Experimental Botany, Vol. 50, No. 339, pp. 1553-1559, 1999.
  51. Gleba, D., Borisjuk, N. V., Borisjuk, L. G., Kneer, R., Poulev, A., Skarzhinskaya, M., Dushenkov, S., Logendra, S., Gleba, Y. Y., and I. Raskin. Use of Plant Roots for Phytoremediation and Molecular Farming. Proc. Natl. Acad. Sci. Vol. 96, No. 11, 5973-5977, 1999.
  52. Pandey, R. C., Yankov, L. K., Poulev, A., Nair, R., and Caccamese, S. Synthesis and Separation of Potential Anticancer Active Dihalocephalomannine Diastereomers from Extracts of Taxus yunnanensis. Journal of Natural Products, Vol. 61, No. 1, 57-63, 1998.
  53. Hylands, P. and A. Poulev. Immunostimulants: Maximizing the Health and Efficiency of Animals through Plant-Derived Biomolecules. In: Biotechnology in the Feed Industry 1994; Proceedings of Alltech's Tenth Annual Symposium. Eds: T. P. Lyons and K. A. Jacques. Nottingham University Press, (1995).
  54. Poulev, A., E. Bombardelli, C. Ponzone and M. H. Zenk. Regioselective Bioconversion of Colchicine and Thiocolchicine into their corresponding 3-Demethyl-Derivatives. Journal of Fermentation and Bioengineering, 79, No. 1, 33-38, (1995).
  55. Poulev, A., B. Deus-Neumann, E. Bombardelli and M. H. Zenk. Immunoassays for the Quantitative Determination of Colchicine. Planta Med., Vol. 60, No. 1, pp. 77-83, (1994).
  56. Poulev, A., B. Deus - Neumann and M. H. Zenk. Enzymeimmunoassay for the Quantitative Determination of Galanthamine. Planta Med., Vol. 59, No. 5, pp. 442-446, (1993).
  57. Tanahashi, T., A. Poulev and M. H. Zenk. Radioimmunoassay for the Quantitative Determination of Galanthamine. Planta Medica 56, 77-81, (1990).
  58. Pulev, A., Velinov, G. Method for the analysis of bicarbonate and acetates in solutions for hemodialysis. Farmatsya (Sofia, Bulgaria, in Bulgarian), 35(5), 1-6, 1985.
  59. Staneva, D., Chakurova, L., Pulev, A. Pharmacological study of 3-alkyl-5-(cycloalcoxymethyl)-oxazolidines. Eksperimentalna Meditsina i Morfologiya (Experimental Medicine and Morphology, in Bulgarian), 21(3), 148-154, 1982.

P A T E N T S

Published Patents: Patent Applications:
  • Ribnicky, D. M., A. Poulev, and I. Raskin. Methods of administering gaultherin-containing compositions. U.S. patent # 7,033,618, April 25, 2006.
  • Ribnicky, D. M., A. Poulev, and I. Raskin. Plant Preparation Containing Phenethylisothiocyanate. Australian Patent No.: 779169, May 2005.
  • Pandey, R., Yankov, L., Nair, R., and A. Poulev. Paclitaxel analogs, preparation and use as antitumor agents. Canadian Patent No.: CA 2210924, March 2004.
  • Ribnicky, D. M., A. Poulev, and I. Raskin. Phenethylisothiocyanate Nutraceutical Compositions and Methods. U.S. patent # 6,348,220, February 19, 2002.
  • Pandey, R. C., L. Yankov, A. Poulev, and R. Nair. Preparation of Chlorinated Paclitaxel Analogues and Use Thereof as Antitumor Agents. U.S. patent # 5,854,278, December 29, 1998.
  • Pandey, R. C., L. Yankov, A. Poulev, and R. Nair. Preparation of Brominated Paclitaxel Analogues and Their Use as Effective Antitumor Agents. U.S. patent # 5,807,888, September 15, 1998.
  • Ribnicky, David M.; Logendra, Sithes; Poulev, Alexander; Cefalu, William T.; and Raskin, Ilya. Compounds from an extract of Artemisia and methods for treating disorders. U.S. patent application # 20070224301, 2007.
  • Raskin, I., and A. Poulev. Elicited plant products. U.S. patent application #20020132021, 2002. Abandoned.
  • Ribnicky, D. M., A. Poulev, and I. Raskin. Recovery of gaultherin from plants. U.S. patent application #20020031562, 2002.

Poster Presentations and Meetings Abstracts:

  1. Satorov, S., Gurdon, C., Poulev, A., Dushenkov, V., and Raskin, I. Development and characterization of high phenolics lettuce varieties as anti-diabetic functional foods. Poster at Fogarty Meeting, NIH, May, 2017.
  2. Gurdon, C., Satorov, S., Poulev, A., Raskin, I. Development and characterization of lettuce lines with novel flavonoid composition. Poster at Rutgers University Postdoc Symposium, Piscataway, NJ, April 28th, 2017.
  3. Rojas-Silva, P., Tümer, T. B., Poulev, A., Raskin, I., Waterman, C. Antioxidant activity of Moringa oleifera isothiocyanates. Poster at the Annual meeting of the American Society of Pharmacognosy, July 25 - 29, Copper Mountain, CO, 2015.
  4. Graf, B. L., Poulev, A., Kuhn, P., Esposito, D., Lila, M. A., Raskin, I. Method to harness bioactive secondary metabolites from intact Quinoa seeds with implications for chronic disease prevention. Poster at the Annual meeting of the American Society of Pharmacognosy, July 25 - 29, Copper Mountain, CO, 2015.
  5. Ribnicky, D. M., Poulev, A., Kuhn, P., Roopchand, D., Oren, A., Havenaar, R., Cefalu, W. T., Raskin, I. The Effect of Formulation on the Bioactivity of Artemisia Preparations for Metabolic Syndrome. Planta Med., Vol. 79, OP4, 2013.
  6. Cheng, D. M., Pogrebnyak, N., Poulev, A., Kuhn, P., Krueger, C. G., Waterman, C., and I. Raskin. Antidiabetic effects and antioxidant capacity of polyphenol enhanced Rutgers Scarlet Lettuce. FASEB J., April 9, 27: 1079.7, 2013.
  7. Cheng, D. M., Pogrebnyak, N., Kuhn, P., Poulev, A., Waterman, C., Rojas-Silva, P., Johnson, W. D., Ribnicky, D., Raskin, I. High Polyphenol Rutgers Scarlet Lettuce Improves Glucose Metabolism and Liver Lipid Accumulation in Diet-Induced Obese Mice. NIH-Botanical Research Centers Annual Meeting. November 2013.
  8. Waterman, C., Cheng, D. M., Rojas-Silva, P., Poulev, A., Raskin, I. Stable, water extractable isothiocyanates from Moringa oleifera leaves mediate inflammation in vitro. NIH-Botanical Research Centers Annual Meeting. November 2013.
  9. Rojas-Silva, P., Graziose, R., Poulev, A., Mbeunkui, F., Grace, M. H., Lila, M. A., Raskin, I. Seeking novel leishmanicidal natural products from common medicinal plants, the example of Eryngium foetidum L. International Congress in Natural Products, American Society of Pharmacognosy (ICNPR). Planta Med., Vol. 78, PF87, New York, NY-USA. July 28 - August 1, 2012.
  10. Graziose, R., Grace, M. H., Rathinasabapathy, Th., Rojas-Silva, P., Dekock, C., Poulev, A., Lila, M. A., Smith, P. J., and I. Raskin. Cucurbitacin glycosides from Datisca glomerata with antiplasmodial activity. Poster presentation at the International Congress on Natural Products Research (ICNPR). Planta Med., Vol. 78, PI452, July 28 - August 1, New York, NY, 2012.
  11. B. Graf, A. Poulev, and I. Raskin. Effect of 20-Hydroxyecdysone on glucose and lipid metabolism in vitro. Implications for the role of Quinoa as a functional food to treat the metabolic syndrome. Poster at the Nutrition, Endocrinology and Animal Sciences Conference, Rutgers University. April 4, New Brunswick, NJ, 2012.
  12. R. Graziose, P. Rojas-Silva, Th. Rathinasabapathy, C. Dekock, A. Poulev, P. Smith, and I. Raskin. Antiparasitic compounds from Cornus florida L. with activities against Plasmodium falciparum and Leishmania tarentolae. Poster at the 50th Anniversary Meeting of the Phytochemical Society of North America, December 10-15, Hilo, Hawaii, USA, 2011.
  13. T. Rathinasabapathy, P. Rojas-Silva, A. Poulev, S. Komarnytsky, and I. Raskin. Isolation of sesquiterpene lactones from roots of Cichorium intybus L. with leishmanicidal activity. Poster at the 50th Anniversary Meeting of the Phytochemical Society of North America, December 10-15, Hilo, Hawaii, USA, 2011.
  14. Esposito, D., Graf, B., A. Poulev, and Raskin, I. Wound Healing Activity of Phytoecdysteroids. Poster at the 50th Anniversary of the Phytochemical Society of North America, Hilo, HI. December 10-15, 2011.
  15. Esposito, D., Th. Rathinasabapathy, A. Poulev, S. Komarnytsky, and I. Raskin. Brassinosteroids increase protein accumulation in skeletal muscle cells. In Vitro Cell. Dev. Biol. - Animal, Vol. 47, Suppl. 1, p. S38, June 2011.
  16. Roopchand, D. E., Kuhn, P., Oren, A., Poulev, A., Ribnicky, D. Lila, M. A. & Raskin, I. Sorption of polyphenols to edible matrices enables natural fortification of foods. 5th International Conference on Polyphenols and Health. Sitges, Spain, October 2011.
  17. Rojo, L. E., Roopchand, D. E., Fridlender, B., Ribnicky, D., Poulev, A., Lila, M. A. and Raskin, I. Maqui Berry Nutrasorb: Creating a natural ingredient from a Chilean Fruit. NEXOS CHILE-USA, Massachusetts Institute of Technology (MIT), Cambridge, MA September 2011.
  18. Roopchand, D. E., Kuhn, P., Oren, A., Poulev, A., Ribnicky, D. Lila, M. A. & Raskin, I. Bioaccessibility and efficacy of blueberry anthocyanins sorbed to protein-rich, food-based matrix. 3rd Annual TIM Symposium. New Brunswick, NJ, September 2011.
  19. Roopchand, D. E., Kuhn, P., Poulev, A., Oren, A., Ribnicky, D. Lila, M. A. & Raskin, I. Anti-diabetic blueberry anthocyanins can be sorbed and stabilized in a protein-rich food-based matrix. 6th International Workshop on Anthocyanins. Concord, NC, September 2011.
  20. Ribnicky, D. M., Poulev, A., Kuhn, P., Roopchand, D. E., Oren, A., Grace, M. H., Yousef, G. G., Havenaar, R., Lila, M. A., Cefalu, W. T., Raskin, I. Effect of carbohydrate matrices on the bioaccessibility and gastric stability of bioactive botanical compounds for metabolic syndrome using the TNO intestinal model. American Association of Cereal Chemists International (AACCI), Palm Springs, CA October 2011.
  21. M. Honarbakhsh, A. Poulev, D. Sannino, A. Gomes, and E. Bini. Occurrence of Antibiotic Resistant Bacteria and Resistance Genes in Wastewater Effluents and Surface Waters. Poster presentation at The Fourth Annual Mini-Symposium on Microbiology at Rutgers University: Cultivate Traditions, Current Strength, and Future Frontiers, New Brunswick, NJ, Feb. 1-2, 2010.

  22. Ribnicky, D. M., Poulev, A., Kuhn, P., Logendra, S., Zuberi, A., Cefalu, W. T., and Raskin, I. A Chalcone from an Extract of Artemisia dracunculus L. Is Glucuronidated In Vivo and Has Antidiabetic Activity Comparable to Metformin. Diabetes, Endocrinology and Metabolism, Vol. 58, p A512, Suppl. 1. Meeting Abstract, American Diabetes Assoc., Alexandria, VA, USA, June, 2009.
  23. Eisenman, Sasha; Poulev, Alexander; Struwe, Lena; Raskin, Ilya. Phytochemical variation in North American populations of wild tarragon (Artemisia dracunculus L.). Joint Annual Meeting of the Mycological Society of America, American Bryological and Lichenological Society, American Fern Society, American Society of Plant Taxonomists, and Botanical Society of America, Botany & Mycology 2009, July 25 - 29, Snowbird, Utah, 2009.
  24. Sithes Logendra, Lucas Chadwick, Nebojša Ilić, Samuel Pro, Alexander Poulev, Jun Ma, Hui Yang, Edward J. Kennelly and Ilya Raskin. Isolation and purification of [6]-paradol from Aframomum melegueta using Fast Centrifugal Partition Chromatography and High Performance Liquid Chromatography. Poster presentation at the 5th international conference on Counter Current Chromatography in Rio-de-Janeiro, Brasil, July 24 - 29, 2008.
  25. Komarnytsky, S., Govorko, D., Esposito, D., O'Neal, J., Poulev, A., and I. Raskin. Pregnane glycosides supress appetite by modulating visceral signaling and glucocorticoid biosynthesis. 1st Annual Endocrine Research Showcase, New Brunswick, NJ, September 8, 2008.
  26. David Ribnicky, Alexander Poulev, Peter Kuhn, Sithes Logendra, Aamir Zuberi, William Cefalu, and Ilya Raskin. Bioavailability assessment of an extract of Artemisia dracunculus L. with antidiabetic activities in vitro and in vivo. Abstract for the 67th Scientific Sessions, American Diabetes Association, June 22 - 26, 2007, Chicago IL, USA.
  27. Barbara M. Schmidt, Moul Dey, Alexander Poulev, Nebojša Ilić, and Ilya Raskin. Isolation and anti-inflammatory activity of the sesquiterpene lactone dihydrolactucopicrin. FASEB J. 21: 701.30, 2007.
  28. Dmitry Govorko, Sithes Logendra, David M. Ribnicky, Alexander Poulev, Jun Ma, Hui Yang, Edward J. Kennelly, and Ilya Raskin. Bioactivity-guided isolation of anti-diabetic compounds from an extract of Artemisia dracunculus L. using a novel PEPCK gene expression assay. Abstract for the 66th Scientific Sessions, American Diabetes Association, June 9 - 13, 2006, Washington DC, USA.
  29. Sithes Logendra, David M. Ribnicky, Alexander Poulev, Jun Ma, Hui Yang, Edward J. Kennelly, and Ilya Raskin. Isolation of novel inhibitors of human aldose reductase activity from an anti-diabetic extract of Artemisia dracunculus L. Abstract for the 66th Scientific Sessions, American Diabetes Association, June 9 - 13, 2006, Washington DC, USA.
  30. Zhong Q. Wang, David M. Ribnicky, Sithes Logendra, Alexander Poulev, Jun Ma, Hui Yang, Edward J. Kennelly, Ilya Raskin, and William T. Cefalu. Bioactives from an extract of Artemisia dracunculus L. exhibit potent inhibitory activities for PTP-1B in human skeletal muscle culture. Abstract for the 66th Scientific Sessions, American Diabetes Association, June 9 - 13, 2006, Washington DC, USA.
  31. David M. Ribnicky, Alexander Poulev, Sithes Logendra, William T. Cefalu, Zhong Wang, and Ilya Raskin. The development of an extract of Artemisia dracunculus for decreasing the insulin resistance associated with diabetes, from concept to clinic. Gordon Research Conference on Agricultural Sciences "Adding more value to production agriculture", February 13 - 18, 2005, Ventura, California, USA. (Download poster in pdf-format).
  32. David M. Ribnicky, Alexander Poulev, Malcolm Watford, Ilya Raskin, Zhong Q. Wang. New Brunswick, NJ; Baton Rouge, LA. The Effect of Tarralin™, an Extract of Artemisia dracunculus L., on Blood Glucose Parameters in Diabetic Animal Models. Abstract for the 64th Scientific Sessions of the American Diabetes Association. June 4 - 8, 2004, Orlando, Florida, USA. (Download poster in pdf-format).
  33. Anita M. Brinker, Alexander Poulev, and Ilya Raskin. Improving the quality and uniformity of botanical drugs: Tripterygium wilfordii, a promising arthritis treatment. (Download poster in pdf-format). Abstract for the University/Industry Workshop Advances in Therapeutic Agents Discovery & Development. January 29, 2002, New Brunswick, NJ, USA.

  34. David M. Ribnicky, Alexander Poulev, and Ilya Raskin. Development of PMI-5001, a Natural Salicylate from Gaultheria procumbens L. for Cardiovascular Health. (Download poster in pdf-format). Abstract for the University/Industry Workshop Advances in Therapeutic Agents Discovery & Development. January 29, 2002, New Brunswick, NJ, USA.

  35. David M. Ribnicky, Ilan Chet, Iris Yedidya, Miriam Abramsky, Dana Frisem, Alexander Poulev, and Ilya Raskin. Extracts of Gaultheria procumbens L. promote disease resistance in Cucumis sativus challenged with Pseudomonas syringae pv. Lachrymans. (Download poster in pdf-format). Abstract for the Annual Meeting of the American Society of Plant Biologists, July 21 - 25, 2001, Providence, RI, USA.

  36. Yankov, L. K., A. Poulev, R. Misra and R. C. Pandey. "Fingerprinting and Quantitation of Bioactive Components in Milk Thistle (Silybum marianum L.) and Its Products Used As Nutraceuticals Using Improved HPLC Method and LC-MS". 41st Annual Meeting of the American Society of Pharmacognosy, July 22-26, 2000 Seattle, WA.
  37. Ribnicky, D., A. Poulev, and I. Raskin. Determination of salicylates in Gaultheria procumbens by LC-MS and GC-MS. (Download poster in pdf-format). Abstract for the Annual Meeting of the American Society of Plant Physiologists, July 24 - 28, 1999, Baltimore, MD, USA.
  38. Yankov, L., R. Nair, A. Poulev, A. Dutta, and R. Pandey. Novel Efficient Process for the Purification of Paclitaxel and Preparation of its Analogues with Anticancer Activity. The Monroe Wall Symposium 'Harnessing Biodiversity for Therapeutic Drugs and Foods: Developing Products for the 21st Century'. June 2 - 5, 1996, New Brunswick, NJ, USA.
  39. Poulev, A., T. Tanahashi and M. H. Zenk. A Radioimmunoassay for the Cholinesterase Inhibitory Alkaloid Galanthamine. 37th Annual Congress of the German Society of Medicinal Plant Research (Gesellschaft für Arzneipflanzenforschung). Planta Med., Vol. 55, No. 7, p. 606, 1 - 5 September 1989, Braunschweig, Germany.
  40. Spassova, M., A. Poulev and A. Atanassov. The Influence of Some Growth Regulators on Tissue Cultures of Solanaceous Medicinal Plants. IV. International Symposium of Plant Growth Regulators. Sept. 28 - 4 Oct. 1986, Pamporovo, Bulgaria.
  41. Spassova, M., A. Poulev and A. Atanassov. Tissue Cultures of Medicinal Plants from Solanaceae. 4th Symposium of the (former) Socialist Countries on Biotechnology. 26 - 30 May 1986, Varna, Bulgaria.