Molecular Systems Bioengineering Laboratory
 

Home

 Personnel Research Teaching News
 

PUBLICATIONS

Refereed Journal Publications

    1. Roth CM, Lenhoff AM.  Electrostatic and van der Waals contributions to protein adsorption:  computation of equilibrium constants.  Langmuir, 1993; 9:962-972.
    2. Roth CM, Lenhoff AM.  Electrostatic and van der Waals contributions to protein adsorption:  comparison of theory with experiment.  Langmuir, 1995; 11:3500-3509.
    3. Roth CM, Neal BL, Lenhoff AM.  Van der Waals interactions involving proteins.  Biophys. J., 1996; 70:977-987.
    4. Roth CM, Unger KK, Lenhoff AM.  A mechanistic model for retention in ion exchange chromatography.  J. Chromatogr., 1996; 726:45-56.
    5. Roth CM, Lenhoff AM.  Improved parametric representation of water dielectric data for Lifshitz theory calculations.  J. Colloid Interface Sci., 1996; 179:637-639.
    6. Roth CM, Reiken SR, Le Doux JM, Rajur SB, Lu X-M, Morgan JR, Yarmush ML.  Targeted antisense modulation of inflammatory cytokine receptors.  Biotechnol. Bioeng., 1997; 55:72-81.
    7. Rajur SB, Roth CM, Morgan JR, Yarmush ML.  Covalent protein-oligonucleotide conjugates for efficient delivery of antisense molecules.  Bioconjugate Chem., 1997; 8:935-940.
    8. Roth CM, Sader JE, Lenhoff AM.  Electrostatic contribution to the energy and entropy of protein adsorption.  J. Colloid Interface Sci., 1998; 203:218-221.
    9. Sundaram S, Roth CM, Yarmush ML.  Pressure-induced dissociation of antigen-antibody complexes.  Biotechnol. Prog., 1998; 14:773-781.
    10. Walton SP, Stephanopoulos GN, Yarmush ML, Roth CM.  Prediction of antisense oligonucleotide binding affinity to a structured RNA target.  Biotechnol. Bioeng., 1999; 65:1-9.
    11. Andreadis ST, Roth CM, Le Doux, JM, Morgan, JR, Yarmush, ML.  Large-scale processing of recombinant retroviruses for gene therapy.  Biotechnol. Prog., 1999, 15:1-11.
    12. Roth CM, Yarmush ML.  Nucleic acid biotechnology.  Annu. Rev. Biomed. Engr., 1999, 1:265-297.
    13. Roy P, Roth CM, Margolies MN, Yarmush ML.  Effect of pressure on antigen-antibody complexes: modulation by ionic strength and temperature.  Mol. Immunol., 1999; 36:1149-1158.
    14. Roy P, Roth CM, Margolies MN, Yarmush ML.  Aromatic residues mediate the pressure-induced association of digoxigenin and antibody 26-10.  Biophys. Chem., 1999; 83:171-177.
    15. Jayaraman A, Yarmush ML, Roth CM.  Dynamics of gene expression in rat hepatocytes under stress.  Metabolic Eng., 2000; 2:239-251.
    16. Roth CM, Kohen RL, Walton SP, Yarmush ML. Coupling of inflammatory cytokine signaling pathways probed by measurements of extracellular acidification rate.  Biophys. Chem., 2001; 89:1-12.
    17. Jayaraman A, Walton SP, Yarmush ML, Roth CM.  Rational selection and quantitative evaluation of antisense oligonucleotides.  Biochim. Biophys. Acta, 2001; 1520:105-114.
    18. Walton SP, Stephanopoulos GN, Yarmush ML, Roth CM.  Thermodynamic and kinetic characterization of antisense oligodeoxynucleotide binding to a structured mRNA.  Biophys. J., 2002; 82:366-377.
    19. Jayaraman A, Yarmush ML, Roth CM.  Molecular bioengineering.  Ind. Eng. Chem. Res., 2002; 41:441-455.
    20. Roth CM.  Quantifying gene expression.  Curr. Issues Mol. Biol., 2002; 4:93-100.
    21. Lee LK and Roth CM.  Antisense technology in molecular and cellular bioengineering.  Curr. Opin. Biotechnol., 2003; 14:505-511.
    22. Roth CM, Sundaram S.  Engineering synthetic vectors for improved DNA delivery: Insights from intracellular pathways.  Annu. Rev. Biomed. Engr., 2004; 6:397-426.
    23. Jayaraman A, Yarmush ML, Roth CM.  Evaluation of an in vitro model of hepatic inflammatory response by gene expression profiling.  Tissue Eng., 2005; 11:50-63.
    24. Roth CM.  Molecular and cellular barriers limiting the effectiveness of antisense oligonucleotides.  Biophys. J., 2005, 89:2286-2295.
    25. Sundaram S, Viriyayuthakorn S, Roth CM.  Oligonucleotide structure influences the interaction between cationic polymers and oligonucleotides.  Biomacromolecules, 2005; 6:2961-2968.
    26. Gevertz JL, Dunn SM, Roth CM.  Mathematical model of real-time PCR kinetics.  Biotechnol. Bioeng., 2005; 92:346-355.
    27. Katz JM, Roth CM, Dunn MG.  Factors that influence transgene expression and cell viability on DNA-PEI seeded collagen films. Tissue Eng., 2005; 11:1398-1406.
    28. Lee LK, Williams CL, Devore D, Roth CM.  Poly(propylacrylic acid) enhances cationic lipid mediated delivery of antisense oligonucleotides.  Biomacromolecules, 2006; 7:1502-1508.
    29. Lee LK, Dunham BM, Li Z, Roth CM.  Cellular dynamics of antisense oligonucleotides and short interfering RNAs.  Ann. N.Y. Acad. Sci., 2006; 1082:47-51.
    30. Moghe PV and Roth CM.  Multidisciplinary graduate curriculum on integrative biointerfacial engineering.  Chem. Eng. Educ., 2006; 40:251-258.
    31. Sundaram S, Lee LK, Roth CM. Interplay of polyethyleneimine molecular weight and oligonucleotide
      backbone chemistry in the dynamics of antisense activity.  Nucleic Acids Res , 2007; 35:4396-4408.
    32. Burley MR, Roth CM. Effects of Retinoic Acid on Proliferation and Differentiation of HepG2 Cells. Open Biotechnology Journal, 2007; 1:47-51.
    33. Roth CM.  Quantitative measurements and rational materials design for intracellular delivery of oligonucleotides.  Biotechnol. Prog., 2008; 24:23-28.
    34. Ierapetritou MG, Georgopoulos PG, Roth CM, Androulakis IP. Tissue-Level Modeling of Xenobiotic Metabolism in Liver: An Emerging Tool for Enabling Clinical Translational Research. Clin. Trans. Sci., 2009; DOI: 10.1111/j.1752-8062.2009.00092.x .
    35. Waite CL, Sparks SM, Uhrich KE, Roth CM. Acaetylation of PAMAM dendrimers for cellular delivery of siRNA. BMC Biotechnol., 2009; 9:38.
    36. Yang H, Roth CM, Ierapetritou MG. A rational design approach for amino acid supplementation in hepatocyte culture. Biotechnol. Bioeng., 2009; PMID: 19422042.

    Book Chapters

    1. Roth CM, Lenhoff AM.  Quantitative modeling of protein adsorption, In:  Malmsten M, ed., Biopolymers at Interfaces.  Marcel Dekker, New York, 1998, pp. 89-118.
    2. Roth CM, Yarmush ML.  Chromatography, size exclusion, In:  Flickinger MC, Drew, SW eds., The Encyclopedia of Bioprocess Technology:  Fermentation, Biocatalysis, & Bioseparation.  John Wiley & Sons, New York, 1999, pp. 639-650.
    3. Walton SP, Roth CM, Yarmush ML.  Antisense technology, In: The Biomedical Engineering Handbook, 2nd ed.  CRC Press LLC, Boca Raton, 2000, Chapter 103, pp. 1-19.
    4. Roth CM.  Electrophoresis: Nucleic acids, In: Encyclopedia of Analytical Science, Second Edition (Paul J. Worsfold, Alan Townshend and Colin F. Poole, eds.), Elsevier, Oxford, 2005, Vol. 2, pp. 456-460.