UMDNJ-Rutgers University
CounterACT Research
Center of Excellence

Designing therapies to counteract chemical terrorism.

 

Mou-Tuan Huang, Ph.D.

Professor
Chemical Biology
Rutgers University

Email: mthuang@rci.rutgers.edu
Room: 113 SLC
Phone: 732-445-3400 x252
Fax: 732-445-0687

B.S.
Ph.D.
Postdoctoral,

Collaborator, UMDNJ-Rutgers University CounterACT Center of Excellence

 

Research Interests:

Wound healing, mechanisms of skin toxicity, cancer chemoprevention, antioxidants, redox cycling, factors influencing tumor initiation and promotion; inflammatory mediators, immunotoxicology, animal models of skin diseases, keratinocyte growth regulation; mechanisms of keratinocyte differentiation

 

 

Recent Publications:

Zheng, X., X. X. Cui, et al. (2010). "Atorvastatin and celecoxib in combination inhibits the progression of androgen-dependent LNCaP xenograft prostate tumors to androgen independence." Cancer Prev Res (Phila Pa) 3(1): 114-24. [abstract]

Cheung, K. L., T. O. Khor, et al. (2009). "Cancer chemoprevention of azoxymethane/dextran sodium sulfate-induced colon carcinogenesis by phenethyl isothiocyanate and dibenzoylmethane." Carcinogenesis. [abstract]

Zheng, X., X. X. Cui, M. T. Huang, Y. Liu, W. J. Shih, Y. Lin, Y. P. Lu, G. C. Wagner and A. H. Conney (2008). "Inhibitory effect of voluntary running wheel exercise on the growth of human pancreatic Panc-1 and prostate PC-3 xenograft tumors in immunodeficient mice." Oncol Rep 19(6): 1583-8. [abstract]

Zheng, X., R. L. Chang, X. X. Cui, G. Avila, M. T. Huang, Y. Liu, A. N. Kong, A. B. Rabson and A. H. Conney (2008). "Inhibition of NF-kappaB by (E)3-[(4-methylphenyl)-sulfonyl]-2-propenenitrile (BAY11-7082; BAY) is associated with enhanced 12-O-tetradecanoylphorbol-13-acetate-induced growth suppression and apoptosis in human prostate cancer PC-3 cells." Int J Oncol 32(1): 257-64. [abstract]

Liu, Y., J. Ju, H. Xiao, B. Simi, X. Hao, B. S. Reddy, M. T. Huang, H. Newmark and C. S. Yang (2008). "Effects of combination of calcium and aspirin on azoxymethane-induced aberrant crypt foci formation in the colons of mice and rats." Nutr Cancer 60(5): 660-5. [abstract]

Khor, T. O., M. T. Huang, A. Prawan, Y. Liu, X. Hao, S. Yu, W. K. Cheung, J. Y. Chan, B. S. Reddy, C. S. Yang and A. N. Kong (2008). "Increased susceptibility of Nrf2 knockout mice to colitis-associated colorectal cancer." Cancer Prev Res (Phila Pa) 1(3): 187-91. [abstract]

Kwon, K. H., A. Barve, S. Yu, M. T. Huang and A. N. Kong (2007). "Cancer chemoprevention by phytochemicals: potential molecular targets, biomarkers and animal models." Acta Pharmacol Sin 28(9): 1409-21. [abstract]

Hong, J., S. J. Kwon, S. Sang, J. Ju, J. N. Zhou, C. T. Ho, M. T. Huang and C. S. Yang (2007). "Effects of garcinol and its derivatives on intestinal cell growth: Inhibitory effects and autoxidation-dependent growth-stimulatory effects." Free Radic Biol Med 42(8): 1211-21. [abstract]

Khor TO, Huang MT, Kwon KH, Chan JY, Reddy BS, Kong AN. Nrf2-deficient mice have an increased susceptibility to dextran sulfate sodium-induced colitis. (2006) Cancer Res, 66(24): 11580-11584. [abstract]

Newmark HL, Huang MT, Reddy BS. Mixed tocopherols inhibit azoxymethane-induced aberrant crypt foci in rats. (2006) Nutr Cancer, 56(1): 82-85. [abstract]

Xu C, Huang MT, Shen G, Yuan X, Lin W, Khor TO, Conney AH, Tony Kong AN. Inhibition of 7,12-Dimethylbenz(a)anthracene-Induced Skin Tumorigenesis in C57BL/6 Mice by Sulforaphane Is Mediated by Nuclear Factor E2-Related Factor 2. (2006) Cancer Res, 66(16): 8293-8296. [abstract]

Li S, Wang Z, Sang S, Huang MT, Ho CT. Identification of nobiletin metabolites in mouse urine. (2006) Mol Nutr Food Res, 50(3): 291-299. [abstract]

 

Copyright © 2008 Joshua P. Gray