RUWINS - Rutgers University Women In Neuroscience

Seminar Series - May 6, 2005

Is there a role for nutrition in inflammation and oxidative stress in aging and disease?

(Paula Bickford)

Paula Bickford, Ph.D.

Professor
Department of Neurosurgery
University of South Florida College of Medicine.
Center for Aging & Brain Repair
Tampa, FL.

Dr. Paula Bickford's research at the Center for Aging and Brain Repair *:

The Center defines excellence in medicine and neuroscience. Furthermore its goals include developing programs combining significant partners related to economics, job development, enhanced recruitment and economic development through corporations, medical groups, and affiliated facilities.



Resent publications*

Albeck, D., Mesches, M.H., Juthberg, S. Browning, M., Bickford, P.C., Rose, G.M., Granholm, A.Ch. Exogenous NGF restores endogenous NGF distribution in the brain of the cognitively impaired aged rat. Brain Res. 967: 306-310, 2003

Cartford, M.C. and Bickford, P.C. The effects of b-adrenergic blockade on acquisition of eyeblink conditioning in 3 month old F344 rats. Neurobiology of Learning and Memory, 78: 246-257, 2002

Cartford, M.C., Gemma, C., and Bickford P.C. Eighteen Month Old F344 Rats fed Spinach-enriched diet show improved Delay Classical eyeblink conditioning and reduced expression of TNF-alpha and TNF-beta in cerebellum, J. Neurosci. 22: 5813-5816, (2002)

Gemma, C., Mesches, M.H., Sepesi,B., Choo, K., Holmes,D.B., Bickford, P.C. Diets enriched in foods with high antioxidant activity reverse age-induced decreases in cerebellar b-adrenergic function and increases in proinflammatory cytokines. J. Neuroscience, 22: 6114-6120, 2002

Newman, MB; Arendash, GW; Shytle, RD; Bickford, PC; Tighe, T; & >Sanberg, PR: Nicotine's oxidative and antioxidant properties in CNS. Life Sciences, 71(24):2807-2820, 2002



* Information taken from the Center for Aging and Brain Repair web site: http://hsc.usf.edu/com/neurosurgery/cabr.html