SYLLABUS

SYLLABUS Revised 9/5/00

Biomaterials Engineering III

Biomaterials Characterization for Tissue Engineering

Rutgers:

• Biomedical Engineering BME #125:553 Section 01 Index # 12360

• Chemical & Biochemical Engineering CBE #155:532 Index # 10669 (Topics in Biochemical Engineering/ Analytical Methods in Tissue Engineering)

Tuesday 2:50-5:50PM FALL 2000

Rutgers LUCY STONE HALL (LSH) - B205 (Livingston Campus);

Rutgers Instructor: Prof. Prabhas Moghe (moghe@rci.rutgers.edu)

The purpose of this course is to provide fundamental instruction on the methods and rationales used in characterization of materials used in cellular bioengineering, tissue engineering and biomedical implant fabrication. It includes instruction in microscopy and imaging techniques, spectroscopy and electron probe methods, mechanical characterization, genetic and biomolecular detection, and quantitative models used to characterize cell and tissue response to biomaterials. It also includes topics such as response of specific tissues to biomaterials, tissue engineering, and artificial organs. Student evaluation will be based on two in-class exams and a biomaterials characterization project. The UMDNJ interface of the course will be directed by Professor John L. Ricci.

Weeks

LECTURE

INSTRUCTORS

& Guest Faculty

1

9/5

Introduction: Overview; Motivation; The state of the art; Defining the problem of biomaterials characterization; Introduction to the problem based structure of the course and discussion of student projects; Contact Angle Measurement of Biomaterial Surfaces

Moghe, Ricci

2

9/12

Method for characterizing Mechanical Properties of Biomaterials & Tissues

Parsons

3

9/19

The Physical basis and operation of Light, Electron, Confocal, Phase Contrast and Fluorescent Microscopes

Moghe

4

9/26

Methods for In Vitro Characterization of Cell-Biomaterial Interface

Moghe

5

10/3

Mathematical Models for Biological Characterization of Materials & Cellular Engineering

Moghe

6

10/10

Physical basis and operation of electron spectroscopy for chemical analysis (ESCA); Electron Microscopy Techniques

Cosandey, Madey

7

10/17

MidTerm Quiz

8

10/24

Methods for In Vivo Characterization of Biomaterials

Ricci

9

10/31

Methods for Characterization of Polymeric Biomaterials (Contd.)

Project Update/Discussion with Instructor

Narasimhan

Moghe, Ricci

10

11/7

Methods for Characterization of Polymeric Biomaterials

Project Update/Discussion with Instructor

Narasimhan

Moghe, Ricci

11

11/14

Methods and Standards for Characterization of Ceramic Biomaterials

Thompson

12

11/28

Methods for Characterization of Genetic and Biomolecular Substrates

Roth/Moghe

13

12/5

Final Quiz and Project Progress Report

Moghe

14

12/12

Break - Project Work

 

15

12/19

Submission of Projects

Moghe

Grading: 2 Quizzes; Attendance at Characterization facilities; Project