125:583 RESEARCH READING AND HOMEWORK (Updated 12/1/06)

BIOINTERFACIAL CHARACTERIZATION

Links for lecture slides and journal papers are given below. Homework for the course involves reading of journal papers to be assigned weekly, followed by a short essay (format: single spaced; one page; figures/references on extra pages) on the principles, insights obtained, shortcomings, of the technique (discussed each week during lecture) in the context of the paper. No formal homework may be assigned on a regular basis.

A case-study will be assigned mid-semester for individual or team report writing and in-class presentations.

#	Date	Topic	Faculty	READING
1	Sep 7, Th	Introduction; Surface Energetics	Moghe	Tziampazis et al., Biomaterials 21:511, 2000 Reserve material set 1 Reserve material set 2
2	Sep 11, M	Cell Adhesive Biointerfaces	Moghe, Shreiber	Baumgartner et al., PNAS 97:4005, 2000
3	Sep 14, Th	Cell Adhesive Biointerfaces II	Moghe, Shreiber	Tan et al., PNAS 100:1484, 2003
4	Sep 18, M	Cell-interactive biointerfaces for cell motility	Moghe	Tjia and Moghe, Tissue Eng, 2:247, 2002 Tjia and Moghe, Annals Biomed. Eng. 30: 851, 2002
5	Sep 21, Th	Elemental characterization of biointerfaces: X-ray photoelectron spectroscopy	Madey, Moghe	Van den Beucken et al., Biomaterials 27: 691, 2006
6	Sep 25, M	XPS Laboratory Demo	Madey	--
	Sep 28, Th	Introduction to spectroscopy	Chabal	--
7	Oct 2, M	Fluorescence spectroscopy	Castner
8	Oct 5, Th	Fluorescence spectroscopy	Castner	Grant et al., Langmuir 21: 1745, 2005
	Oct 9, M	Fluorescence spectroscopy demos	Castner Lab
9	Oct 12, Th	FTIR spectroscopy	Chabal
10	Oct 16, M	FTIR spectroscopy	Chabal	Cheng et al., J. Coll. Surf. Sci., 162: 135, 1994
	Oct 19, Th	FTIR laboratory demos	Chabal
	Oct 23, M	Test 1
11	Oct 26, Th	Light Microscopy Techniques for Biomaterials and Cell Based Interfaces Assignment of Case Studies	Moghe	Chang et al., Biomaterials 20:273, 1999 Liu et al., JBMR, In Press, 2006
12	Oct 30, M	Protein-protein interactions	Brewer	Piehler, Curr. Opin. Str. Biol. 15:4., 2005 Gavin et al., Nature 415: 141, 2002 Other referenced papers: PDF1, PDF2, PDF3, PDF4, PDF5
13	Nov 2, Th	Molecular Modeling I	Welsh	Smith et al., Polymer 46: 4296, 2005
14	Nov 6, M	Molecular Modeling II	Welsh	Sun et al., Langmuir 21: 5616, 2005
15	Nov 9, Th	No lecture (NJCBM Symposium)
16	Nov 13, M	Proteins/Biomolecules on Substrates	Moghe	Rezania et al., Langmuir 19: 6931, 1999 Lehman et al., J. Chromatogr. B 808: 43, 2005
17	Nov 16, Th	Physicochemical characterization of bio-nanoparticles	Anthony	Chnari et al., Biomaterials 26: 3749, 2005 Langer et al., Int. J. Pharm 257: 169, 2003 Other referenced materials: PDF1, PDF2, PDF3 PDF4, PDF5
	Nov 20, M	Lab Demo -- Nanoparticle Characterization	Anthony
18	Nov 23, Th	Thanksgiving Break	Kim
	Nov 27, M	Protein Arrays; Protein Chips Demo on MALDI-TOF Spectrometry		Zhu et al., Science 293:2101, 2001 Reddy and Dalmasso, J. Biomed. Biotechnol 4: 237, 2003
19	Nov 30, Th	Lab Demo: Confocal Microscopy/Atomic Force Microscopy	Moghe
	Dec 4, M	Biological Characterization of Nanoparticles	Moghe	Popielarski et al., Bioconj. Chem. 16: 1063, 2005 Irvine et al., Biomacromolecules 2: 545, 2001 Maheshwari et al., J. Cell Sci 113: 1677, 2000
	Dec 7, Th	Preparation of Term Papers	Moghe
	Dec 11, M	Term Paper Presentations (In Class)	Moghe