Michniak-Kohn, Bozena B.
Ph.D., De Montfort University, U.K., 1980
Professional Summary/CV [.PDF]
Department of Pharmaceutics, Ernest Mario School of Pharmacy, New Brunswick; Rutgers
Areas of Interest
Topical and transdermal drug delivery.
Memberships and Professional Service
Director for the Industrial Membership Program of the NJCBM; serves on the Industrial Advisory Board Steering Committee (IABSC) of the NJCBM; reviewer on NIH Study Sections “Gene and Drug Delivery”; ERC Liaison to the FDA; Fellow of the American Association of Pharmaceuticakl Scientists. (AAPS).
Grants, Honors, and Awards
Meggers Award from the Society for Applied Spectroscopy for paper entitled “Infrared Kinetic/Structural Studies of Barrier Reformation in Intact Stratum Corneum Following Thermal Perturbation” Applied Spectroscopy, 2007; Chair 2007 and Vice Chair 2006 of the American Association of Pharmaceutical Scientists (AAPS) Student and Post Doc Outreach and Development Committee (SPOD); Consulting Editor for the American Journal of Drug Delivery-Adis Press, 2004-2006.
Academic Interests and Plans
The main focus of my research group is in the area of topical and transdermal drug delivery. Part of the work is devoted to the tissue engineering of skin, and a human skin co-culture of fibroblasts and keratinocytes using collagen as a dermal matrix, has been developed and been shown to possess similar drug permeability to human skin. The aim is to develop this bioengineered human skin as a screen for examining skin barrier properties, as well as a model for inflammatory and cytotoxicity testing. In addition, projects include the design of transdermal and buccal patches for the U.S. Army, development of a novel microneedle transdermal delivery system, and iontophoretic delivery of drugs with and without additional chemical enhancement. Additional studies involve the effects of protective barrier creams on the penetration of chemical warfare agent mimics using various skin models.
In addition we are investigating drug transport in novel polymer membranes as well as uterine/vaginal and buccal tissue models. We are also part of a group of the $15M Rutgers NSF Engineering Research Center examining the scientific foundation, based on a predictive understanding of structure-function-performance relationships, for the optimal design of structured organic composites with advanced functionality.