Brzustowicz, Linda M.
M.D., Colombia University, 1987
Professional Summary/CV [.PDF]
Department of Genetics, School of Arts and Sciences, New Brunswick; Rutgers
Areas of Interest
Gene function in both the pathologic and normal states. Genetics of schizophrenia, autism, and specific language impairment (SLI).
Human Genetics, Medical Genetics.
Memberships and Professional Service
Motif BioSciences Scientific Advisory Board, 2004 - present; AstraZeneca Schizophrenia Genetics Advisory Board, 2003; New Jersey Tourette Center of Excellence, Scientific Advisory Board, 2005 – present; Fragile Families (Princeton University) DNA Advisory Group, 2007 – present; Department of Defense Autism Spectrum Disorder Research Program Integration Panel, 2007. Memberships: New York Academy of Sciences, International Genetic Epidemiology Society, American Society of Human Genetics, American Psychiatric Association, American Association for the Advancement of Science.
Linda with two DNA sequencing plates, 2007.
Grants, Honors, and Awards
National Institute of Health and National Institute off mental health grants: Elucidating the Role of miRNA Dysregulation in Schizophrenia and Bipolar Disorder, 2007-2012; Identification and Functional Assessment of Autism Susceptibility Genes,2005-2010; Molecular Genetics of Schizophrenia Susceptibility, 2004-2009, Genetic Components of Autism Spectrum Disorders, 2003-2008; March of Dimes Research Award, Genetic Studies of Language and Reading Impairment in Canadian Families, 2002-2007; NARSAD Staglin Family Music Festival Schizophrenia Research Award, 2005; NARSAD Independent Investigator Award, 2000; New York State Psychiatric Institute, Centennial Award, Alumna of the Decade, 1990s, 1994; New York State Psychiatric Institute Alumni Award for Research, 1994.
Academic Interests and Plans
My research group applies the techniques of molecular and statistical genetics to approach clinically relevant problems in neuroscience, with the ultimate goal of understanding gene function in both the pathologic and normal states. We are currently studying schizophrenia, autism, and specific language impairment (SLI). Work directly conducted by my group includes development of phenotype definitions, subject recruitment and assessment (for autism and SLI), genotyping and statistical analysis for linkage and association studies, comparative genomic analysis, and gene expression studies. Other areas of particular interest include the role of microRNAs in the control of gene expression in the human brain and enhancements to moderately high throughput genotyping technologies. Our primary collaborators outside of Rutgers/UMDNJ are Dr. Anne Bassett at the University of Toronto, who works on phenotype definition, subject recruitment and assessment for schizophrenia, and Dr. Veronica Vieland at the University of Ohio, who works on the development of advanced statistical genetics methods.